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UV-LED/P25-based photocatalysis for effective degradation of isothiazolone biocide

《环境科学与工程前沿（英文）》 2021年 第15卷 第5期 doi: 10.1007/s11783-020-1379-x

摘要：

• UV-LED with shorter wavelength was beneficial for photocatalytic degradation.

关键词： Degradation     Photocatalytic     LED     CMIT     P25    

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Assessing combined toxic effects of tetracycline and P25 titanium dioxide nanoparticles using

Barsha Roy, Khushboo Kadam, Suresh Palamadai Krishnan, Chandrasekaran Natarajan, Amitava Mukherjee

《环境科学与工程前沿（英文）》 2021年 第15卷 第1期 doi: 10.1007/s11783-020-1298-x

摘要： Abstract • UVA pre-irradiation to TiO2 NPs enhanced its toxicity toward plant A. cepa. • UVA TiO2 NPs increased intracellular ROS, resulting in more cell damage. • Cell death enhanced cell permeability and increased uptake of NPs. • Being highly toxic (EC50 = 0.097 µmol/L), TC did not increase ROS generation. • Even at a low dose, TC enhanced the toxic potential of TiO2 NPs significantly. Usage of titanium dioxide nanoparticles (TiO2 NPs) and tetracycline (TC) has increased significantly in the present era. This leads to their release and accumulation in the environment. Both the compounds, individually, can have adverse toxic effects on the plants. Their binary mixtures can increase this degree of damage. The present study aimed to evaluate the toxicity of both the contaminants in individual and binary mixtures in Allium cepa. Further, the toxicity of TiO2 NPs upon UVA pre-irradiation was also measured. Results showed that UVA pre-irradiated NPs (UVA-TiO2 NPs) had a significant decrease in cell viability than their non-irradiated counterparts (NI-TiO2), denoting an increase in photocatalytic activity upon UVA pre-irradiation. Very low concentrations of TC (EC10 = 0.016 µmol/L) mixed with TiO2 NPs significantly increased the toxicity for both UVA-TiO2 and NI-TiO2 NPs. Intracellular ROS generation was significantly high for UVA-TiO2 NPs. However, TC did not have any effects on ROS production. Both the compounds exhibited genotoxic potential in A. cepa. Different chromosomal abnormalities like anaphase bridges, telophase bridges, laggard chromosomes, binucleate cells, etc. were observed. The binary mixture of UVA-TiO2 NPs and TC showed the highest chromosomal aberrations (64.0%±1.26%) than the mixture with NI-TiO2 or the individual contaminants. This decreased significantly after recovery (46.8%±1.92%), denoting the self-repair processes. This study proved that UVA-TiO2 NPs were more toxic and could be enhanced further when mixed with a sub-lethal concentration of TC. This work will help to assess the risk of both compounds in the environment.

关键词： Binary toxicity     Cell viability     Mitotic index     Chromosomal aberration     Reactive oxygen species     Nanoparticles internalization    

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Preface to the CSCST-25 Special Issue

Xiaolei Fan, Jiawei Wang

《化学科学与工程前沿（英文）》 2019年 第13卷 第4期   页码 629-631 doi: 10.1007/s11705-019-1903-3

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Changes of phenotype and function of human CD4 CD25 T cells induced by transfection of Foxp3

WU Kui, BI Yutian, WANG Yaoli, WANG Changzheng

《医学前沿（英文）》 2008年 第2卷 第4期   页码 366-369 doi: 10.1007/s11684-008-0070-6

摘要： The aim of this paper is to explore the effects of transfection of Foxp3 gene on the phenotype and function of naive CD4 T cells. The pMSCV-Foxp3 retroviral vector encoding Foxp3 gene was transduced into the PT67 packaging cell line. Virus-containing supernatant was applied to differentiate CD4CD25 T cells. The resulting cells were sorted with flow cytometry. The expressions of CD25, CD127, CTLA-4 and the proliferation of transfected T cells were examined. The effect of transfected CD4 T cells on the proliferation and cytokine production of CD4CD25 T cells was examined. Foxp3-gene transfected CD4 T cells could express Foxp3 and transfection of Foxp3 gene up-regulated the expressions of CD25 and CTLA-4, but down-regulated CD127 expression. After transfection, the proliferation of CD4 T cells was eliminated. Transfected T cells inhibited the proliferation of CD4CD25 T cells. CD4CD25 T cells acquired a regulatory phenotype and function after it was transduced with the Foxp3 gene. This suggested a key role of Foxp3 in the generation of CD4CD25 regulatory T cells.
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Biological features of intrahepatic CD4+CD25+ T cells in the naturally tolerance of rat liver transplantation

LU Ling, ZHANG Feng, PU Liyong, YAO Aihua, YU Yue, SUN Beicheng, LI Guoqiang, WANG Xuehao

《医学前沿（英文）》 2007年 第1卷 第4期   页码 373-376 doi: 10.1007/s11684-007-0072-9

摘要： The biological features of intrahepatic CD4CD25 T regulatory cells in the naturally tolerance of rat liver transplantation were explored. Orthotopic liver transplantation was performed in two allogeneic rat strain combinations, one with fatal immunosuppression despite a complete major histo compatibility complex mismatch. The subjects were divided into three groups according to different donors and recipients [Tolerance group: LEW-to-DA; Rejection group: DA-to-LEW; Syngegnic group (control group): DA-to-DA]. The proportion of intrahepatic CD4CD25 T cells from three groups was determined by flow cytometry (FCM) in different time. The intrahepaitc CD4CD25 T cells were isolated by magnetic activated cell sorting (MACS) method and iden tified by FCM. The Foxp3 mRNA was detected by reverse transcriptase polymerase chain reaction (RT-PCR). And their suppression on the proliferation of CD4CD25 T effector cells was analyzed by cell proliferation assay . Beginning immediately after transplantation, the proportion of Treg cells increased over time in both allogeneic groups but was significantly greater in the Rejection group. The proportion of Treg cells declined after day 5, and such reduction was more dramatic in the Rejection group than in the Tolerance group. Animals in the Tolerance group showed a second increase in the proportion after day 14. Intrahepatic CD4CD25 T cells isolated from spontaneous tolerance models inhibited the proliferation of mixed lymphocyte reaction. The purity of CD4CD25 T cells sorted by MACS was 86%–93%. The CD4CD25 T cells could specifically express the Foxp3 gene compared with CD4CD25 T cells. , the spleen cells from LEW rats can irritate the proliferation of CD4CD25 T cells more obviously than the syngegnic spleen cells. CD4CD25 Tr cells could suppress the proliferation of CD4CD25 T cells, but the inhibition was reversed by exogenous IL-2 (200 U/mL). The CD4CD25 T regulatory cells specifically express the Foxp3 gene, which may play an important role in the induction of liver transplantation tolerance by suppressing the reaction of effective T cells.

关键词： magnetic     LEW-to-DA     effector     MACS     cytometry    

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1.3-μm 4×25-Gb/s混合集成收发光子组件 Special Feature on Optoelectronic Devices and Inte

Yu LIU, Hao-tian BAO, Yi-ming ZHANG, Zhi-ke ZHANG, Yun-shan ZHANG, Xiang-fei CHEN, Jun LU, Yue-chun SHI

《信息与电子工程前沿（英文）》 2019年 第20卷 第4期   页码 490-497 doi: 10.1631/FITEE.1800371

摘要： 介绍了一种采用混合集成技术的小型低成本4×25-Gb/s收发光子组件（TOSA/ROSA）的设计与制造。TOSA和ROSA在无热电冷却器（TEC）情况下可满足粗波分复用（CWDM）应用。

关键词： 重建等效啁啾；阵列式光波导；发射机光学组件；混合集成    

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P2P energy trading via public power networks: Practical challenges, emerging solutions, and the way forward

《能源前沿（英文）》 2023年 第17卷 第2期   页码 189-197 doi: 10.1007/s11708-023-0873-9

摘要： Peer-to-peer (P2P) energy trading is an emerging energy supply paradigm where customers with distributed energy resources (DERs) are allowed to directly trade and share electricity with each other. P2P energy trading can facilitate local power and energy balance, thus being a potential way to manage the rapidly increasing number of DERs in net zero transition. It is of great importance to explore P2P energy trading via public power networks, to which most DERs are connected. Despite the extensive research on P2P energy trading, there has been little large-scale commercial deployment in practice across the world. In this paper, the practical challenges of conducting P2P energy trading via public power networks are identified and presented, based on the analysis of a practical Local Virtual Private Networks (LVPNs) case in North Wales, UK. The ongoing efforts and emerging solutions to tackling the challenges are then summarized and critically reviewed. Finally, the way forward for facilitating P2P energy trading via public power networks is proposed.

关键词： distribution network     local virtual private network     network charges     peer-to-peer (P2P) energy trading     practical implementation.    

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Solomon P Wasser：蕈菌的药用（2019年9月19日）

Solomon P Wasser(高级职称)

2021年01月20日

关键词： 农业科学    

面向服务的P2P网络体系结构层次参考模型研究

刘业,刘林峰,庄艳艳

《中国工程科学》 2007年 第9卷 第9期   页码 72-77

摘要： <p style="text-align: justify;">提出了一种基于交互、 面向服务的P2P网络体系结构框 架模型ISPNA，同时结合P2P网络 松耦合、自组织、可缩放等特点， 对P2P网络技术中增强其可用性需从P2P网络体系结构的研究角度出发， 将增强P2P网络可用性所需要考虑的 多方面因素放置在P2P网络的不同 层次予以解决，有利于从宏观上 把握需要解决的问题。p>

关键词： P2P网络     体系结构     层次参考模型     资源     服务    

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Probes and nano-delivery systems targeting NAD(P)H:quinone oxidoreductase 1: a mini-review

《化学科学与工程前沿（英文）》 2023年 第17卷 第2期   页码 123-138 doi: 10.1007/s11705-022-2194-7

摘要： The two-electron cytoplasmic reductase NAD(P)H:quinone oxidoreductase 1 is expressed in many tissues. NAD(P)H:quinone oxidoreductase 1 is well-known for being highly expressed in most cancers. Therefore, it could be a target for cancer therapy. Because it is a quinone reductase, many bioimaging probes based on quinone structures target NAD(P)H:quinone oxidoreductase 1 to diagnose tumours. Its expression is higher in tumours than in normal tissues, and using target drugs such as β-lapachone to reduce side effects in normal tissues can help. However, the physicochemical properties of β-lapachone limit its application. The problem can be solved by using nanosystems to deliver β-lapachone. This mini-review summarizes quinone-based fluorescent, near-infrared and two-photon fluorescent probes, as well as nanosystems for delivering the NAD(P)H:quinone oxidoreductase 1-activating drug β-lapachone. This review provides valuable information for the future development of probes and nano-delivery systems that target NAD(P)H:quinone oxidoreductase 1.

关键词： NAD(P)H:quinone oxidoreductase 1     cancer therapy     target     probe     nanosystem    

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Fine-grained P2P traffic classification by simply counting flows

Jie HE,Yue-xiang YANG,Yong QIAO,Wen-ping DENG

《信息与电子工程前沿（英文）》 2015年 第16卷 第5期   页码 391-403 doi: 10.1631/FITEE.1400267

摘要： The continuous emerging of peer-to-peer (P2P) applications enriches resource sharing by networks, but it also brings about many challenges to network management. Therefore, P2P applications monitoring, in particular, P2P traffic classification, is becoming increasingly important. In this paper, we propose a novel approach for accurate P2P traffic classification at a fine-grained level. Our approach relies only on counting some special flows that are appearing frequently and steadily in the traffic generated by specific P2P applications. In contrast to existing methods, the main contribution of our approach can be summarized as the following two aspects. Firstly, it can achieve a high classification accuracy by exploiting only several generic properties of flows rather than complicated features and sophisticated techniques. Secondly, it can work well even if the classification target is running with other high bandwidth-consuming applications, outperforming most existing host-based approaches, which are incapable of dealing with this situation. We evaluated the performance of our approach on a real-world trace. Experimental results show that P2P applications can be classified with a true positive rate higher than 97.22% and a false positive rate lower than 2.78%.

关键词： Traffic classification     Peer-to-peer (P2P)     Fine-grained     Host-based    

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Q&P 工艺理念在热轧先进高强度钢中的应用研究

袁国,康健,张贺,李云杰,胡虹玲,王国栋

《中国工程科学》 2014年 第16卷 第1期   页码 59-65

摘要： <p>为满足汽车工业轻量化发展要求，以Q&P（quenching & partitioning）工艺为基础的先进高强度钢受到了广泛关注，为使其在普通热连轧生产线上实现工业化并广泛应用，本文对Q&P理念在热轧工艺中的应用进行了基础研究。结果表明在传统热处理Q&P工艺中引入热变形处理后，组织细化显著，并获得了一定量的残余奥氏体。）&P钢）的可行性。p>

关键词： 先进高强度钢     Q&P     DQ&P     热轧     残余奥氏体    

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Comparison of modeling methods for wind power prediction: a critical study

Rashmi P. SHETTY, A. SATHYABHAMA, P. Srinivasa PAI

《能源前沿（英文）》 2020年 第14卷 第2期   页码 347-358 doi: 10.1007/s11708-018-0553-3

摘要： Prediction of power generation of a wind turbine is crucial, which calls for accurate and reliable models. In this work, six different models have been developed based on wind power equation, concept of power curve, response surface methodology (RSM) and artificial neural network (ANN), and the results have been compared. To develop the models based on the concept of power curve, the manufacturer’s power curve, and to develop RSM as well as ANN models, the data collected from supervisory control and data acquisition (SCADA) of a 1.5 MW turbine have been used. In addition to wind speed, the air density, blade pitch angle, rotor speed and wind direction have been considered as input variables for RSM and ANN models. Proper selection of input variables and capability of ANN to map input-output relationships have resulted in an accurate model for wind power prediction in comparison to other methods.

关键词： power curve     method of least squares     cubic spline interpolation     response surface methodology     artificial neural network (ANN)    

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noncoding RNA LOC646029 functions as a ceRNA to suppress ovarian cancer progression through the miR-627-3p/

《医学前沿（英文）》   页码 924-938 doi: 10.1007/s11684-023-1004-z

摘要： Long noncoding RNAs (lncRNAs) play a crucial regulatory role in the development and progression of multiple cancers. However, the potential mechanism by which lncRNAs affect the recurrence and metastasis of ovarian cancer remains unclear. In the current study, the lncRNA LOC646029 was markedly downregulated in metastatic ovarian tumors compared with primary tumors. Gain- and loss-of-function assays demonstrated that LOC646029 inhibits the proliferation, invasiveness, and metastasis of ovarian cancer cells in vivo and in vitro. Moreover, the downregulation of LOC646029 in metastatic ovarian tumors was strongly correlated with poor prognosis. Mechanistically, LOC646029 served as a miR-627-3p sponge to promote the expression of Sprouty-related EVH1 domain-containing protein 1, which is necessary for suppressing tumor metastasis and inhibiting KRAS signaling. Collectively, our results demonstrated that LOC646029 is involved in the progression and metastasis of ovarian cancer, which may be a potential prognostic biomarker.

关键词： ovarian cancer     lncRNA LOC646029     metastasis     microRNA 627-3p     SPRED1    

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标题 作者 时间 类型 操作

UV-LED/P25-based photocatalysis for effective degradation of isothiazolone biocide

期刊论文

Assessing combined toxic effects of tetracycline and P25 titanium dioxide nanoparticles using

Barsha Roy, Khushboo Kadam, Suresh Palamadai Krishnan, Chandrasekaran Natarajan, Amitava Mukherjee

期刊论文

Preface to the CSCST-25 Special Issue

Xiaolei Fan, Jiawei Wang

期刊论文

Changes of phenotype and function of human CD4 CD25 T cells induced by transfection of Foxp3

WU Kui, BI Yutian, WANG Yaoli, WANG Changzheng

期刊论文

Biological features of intrahepatic CD4+CD25+ T cells in the naturally tolerance of rat liver transplantation

LU Ling, ZHANG Feng, PU Liyong, YAO Aihua, YU Yue, SUN Beicheng, LI Guoqiang, WANG Xuehao

期刊论文

1.3-μm 4×25-Gb/s混合集成收发光子组件

Yu LIU, Hao-tian BAO, Yi-ming ZHANG, Zhi-ke ZHANG, Yun-shan ZHANG, Xiang-fei CHEN, Jun LU, Yue-chun SHI

期刊论文

construction integration technology in Brazil’s superlarge deep-water offshore oil and gas unit project (FPSO P67/P70)

期刊论文

P2P energy trading via public power networks: Practical challenges, emerging solutions, and the way forward

期刊论文

Solomon P Wasser：蕈菌的药用（2019年9月19日）

Solomon P Wasser(高级职称)

2021年01月20日

会议视频

面向服务的P2P网络体系结构层次参考模型研究

刘业,刘林峰,庄艳艳

期刊论文

Probes and nano-delivery systems targeting NAD(P)H:quinone oxidoreductase 1: a mini-review

期刊论文

Fine-grained P2P traffic classification by simply counting flows

Jie HE,Yue-xiang YANG,Yong QIAO,Wen-ping DENG

期刊论文

Q&P 工艺理念在热轧先进高强度钢中的应用研究

袁国,康健,张贺,李云杰,胡虹玲,王国栋

期刊论文

Comparison of modeling methods for wind power prediction: a critical study

Rashmi P. SHETTY, A. SATHYABHAMA, P. Srinivasa PAI

期刊论文

noncoding RNA LOC646029 functions as a ceRNA to suppress ovarian cancer progression through the miR-627-3p/

期刊论文